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Simcyp



Description

Simcyp Limited is a research-based company with an international reputation for high quality scientific input into the drug development process. Simcyp Limited has developed a platform for modelling and simulation of drug absorption, distribution, metabolism and excretion (ADME) in virtual populations. The Simulator is licensed to their Consortium member clients for use in drug discovery and development and is also provided free of charge to academic institutions for research and teaching. Simcyp maintains strong academic links and their science team conducts internationally recognised cutting-edge research and development. They also offer consultancy services and run education programmes around the world. The Simcyp team published numerous papers each year in relation to in vitro-in vivo extrapolation, pharmacokinetic modelling, building physiologically based models and linical pharmacology.

 

Persons

Devendra Pade This e-mail address is being protected from spambots. You need JavaScript enabled to view it

Devendra Pade is a research scientist at Simcyp Limited. His work at Simcyp focuses on physiologically based pharmacokinetic (PBPK) models and prediction of pharmacokinetic profiles in human, dog, rat and mice using IVIVE. His role in the project will be to analyse and assimilate data relevant to transport of drugs across the BBB and BCSFB. The aim is to incorporate these data later into mathematical models of drug transport across the BBB.

Karen Rowland Yeo

Karen Rowland Yeo is Head of Bioinformatics at Simcyp. Her role will be in relation to quality assurance of data going into the BBB model and in the performance verification of the final model.

Gaohua Lu This e-mail address is being protected from spambots. You need JavaScript enabled to view it

Gaohua Lu is interested in drug transporters. His role will be to collect data on drug transporters that can be incorporated into a physiologically based model. This will involve close liaison with other work package leaders and research groups involved in the project.

Fania Bajot This e-mail address is being protected from spambots. You need JavaScript enabled to view it

Fania Bajot is interested in drug transport. Her role will be to collect data on drug transporters that can be incorporated into a physiologically based model. She will also assist in validating and testing of mathematical models of drug transport across the BBB.

 

Contact

Simcyp Limited

Blades Enterprise Centre
John Street
Sheffield, S2 4SU
UK

www.simcyp.com

 



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Funded by the European Commisssion under the grant agreement n° HEALTH-F2-2009-241778.